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Addition of light scattering agents in contrast to the abovementioned design led to a significant increase in the release of the imaging dyes (Fig. 6). The herein presented data show that the effectiveness of light-scattering agents strongly depends on the shape and orientation of cavities. The addition of light-scattering agents to devices with rhomboid-shaped cavities (design 1) increased the release rate by 2.7 times, compared to the release rate of devices without light-scattering agents (design 0). At the same time, no evident changes in the release rate were observed when devices with circular cavities (design 2) were equipped with light-scattering agents (Fig. 6). The most evident changes in the release rate were seen in devices with grating-shaped cavities (design 4). A significant increase in the release rate of the dye was detected with the addition of light-scattering agents to devices with grating-shaped cavities (design 4): a threefold increase in the release rate was observed compared to the release rate of devices without light-scattering agents (design 3).

The results obtained for devices with grating-shaped cavities, with and without light-scattering agents, are comparable to the release rates of dyes loaded in devices of the same design, but without light-scattering agents (Fig. 6 and Table 1). In contrast, the incorporation of light-scattering agents to devices with rectangular or circular cavities (design 0, 2), led to a decrease in the release rate of the dye (Fig. 6 and Table 1). On the whole, both the shape of cavities and the addition of light-scattering agents had a significant effect on the release profile. The data show that light-scattering agents can be used to increase the release rate of the dye while maintaining the shape of cavities.

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